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  1. Home |
  2. Advancing Health Research

Research Case Studies

Case study examples of how we have enabled research across the UK.

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Case study

Four-nations study showed vaccine protection against severe COVID-19 outcomes wanes over time

28 February 2023

Researchers, part of the EAVE II programme, analysed data from 12.9 million individuals across the UK to explore the effectiveness of COVID-19 vaccines.

Case study

Vital research that helped identify the priority groups for COVID-19 boosters

28 February 2023

Research part-funded by HDR UK provided a detailed population-level analysis which was invaluable in guiding vaccine prioritisation decisions.

Case study

Feasibility and ethics of using data from the Scottish newborn blood spot archive for research

28 February 2023

The HDR UK Impact Commitee selected a paper by Cunningham-Burley et al as the Open Impact Publication of the Month.

Case study

New research questions reliability of studies into Lassa fever drug

28 February 2023

Researchers identified and re-analysed a series of studies to assess the reliability of the evidence backing the use of ribavirin as a treatment for Lassa fever.

Case study

CogStack information retrieval and extraction platform

27 February 2023

CogStack represents a major advance in the capacity to extract and analyse unstructured data from electronic health records (EHRs). It uses a range of technologies to support modern open-source...

Case study

Biobank conversion allows greater UK contribution to international research

21 February 2023

A team of researchers processed and converted over 1.3 billion rows of UK Biobank data to the Observational Medical Outcomes Partnership (OMOP) common data model (CDM), improving its usability for...

Case study

Multi-generational households, living alone and ethnicity – older people and the risk of severe COVID-19 outcomes

21 February 2023

Researchers carried out an analysis of older people and the risk of severe COVID-19 outcomes using the OpenSAFELY research platform

Case study

New advances in understanding long COVID

20 February 2023

Researchers analysed the primary healthcare records of 7.4 million patients in England to develop a long COVID phenotype, strengthening further research to improve the understanding of the condition.

Case study

Paving the way for quicker, simpler and less expensive use of scans to diagnose heart damage

20 February 2023

Researchers have applied machine learning to improve the detection of heart damage through cardiac magnetic resonance (CMR) scans.

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