Research Case Studies
Case study examples of how we have enabled research across the UK.
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Evaluation of antithrombotic use and COVID-19 outcomes in a nationwide atrial fibrillation cohort
Our Open Access Publication of the Month, May: Selected by the Impact Committee for its research excellence
Accelerating research through data-enabled Clinical Trials
Linking historic trial data with electronic health records allowed this dormant trial on the relationship between infant formula and cognitive ability to become reactivated - making it the first...
Ethnicity and COVID-19: investigating the determinants of excess risk
Early on in the pandemic, reports started emerging that ethnic minority groups were at greater risk of COVID-19. This project looked at data from healthcare records and linked it to national...
The relative contributions of different exposures and settings to COVID-19 community transmission
Analysis of community cohort studies linked to national testing data to understand how COVID-19 spreads at home, work, school and other public places and if this is affected by age, ethnic...
How COVID-19 has impacted women and men’s working lives in the UK
The pandemic changed the way we work. This project looked to understand how the pandemic impacted the working lives of women and men differently, focusing on job loss, precarious work and...
Using national data to understand how palliative and end of life care services responded during the Covid-19 pandemic
The Covid-19 pandemic continues to cause a huge strain on health care services, including palliative care, which aims to control symptoms and reduce suffering when patients cannot be cured. This...
Enabling harmonised, near real-time, data on pharmacovigilance of COVID-19 vaccines using routinely collected linked national datasets across the UK
Researchers used national data sets to answer questions at the start of the pandemic about who was being vaccinated, what kind of protection from COVID-19 they offered, and how safe they were on a...
COVID-19 vaccine uptake, effectiveness, and waning in 82,959 health care workers: A national prospective cohort study in Wales
Understanding the effectiveness and uptake of the COVID-19 vaccines in the population was a vitally important area of study as the rollout progressed. This was particularly the case for the most...
Do home adaptation interventions help to reduce emergency fall admissions? A national longitudinal data-linkage study of 657,536 older adults living in Wales (UK) between 2010 and 2017
Falls are a significant concern for older people and the NHS, however there is little evidence for the effectiveness of services to make adaptations at home. Researchers in Wales have used health...