Project supervisor: Dr Jinming Duan
Internship mode: Flexible, to be agreed with scholar
Cardiovascular MR (CMR) imaging enables quantification of the heart, which are crucial for diagnosing, assessing and monitoring cardiovascular diseases (CVDs). A limitation of CMR is the slow acquisition time, which makes the tool costly and less accessible to worldwide population. Accelerating the CMR acquisition is therefore essential. However, reconstructing high-quality images from accelerated CMR acquisition is a non-trivial problem. Another limitation is quantitative analysis of reconstructed CMR images requires the development of separate post-processing methods. The resulting quantification can be inaccurate if the
reconstruction contains errors.
As such, we aim to develop end-to-end, optimal AI and machine learning approaches that bypass the usual image reconstruction stage, therefore improving both the CMR acquisition time and quantification accuracy. The key insight here is that in many cases the images are not an end in themselves, but rather the means of accessing clinically relevant parameters. Therefore, it is more effective to instead combine reconstruction and post-processing steps and learn an end-to-end, optimal model that directly calculates final results as accurately and efficiently as possible. Consequently, patients with CVDs is poised to benefit from fast yet accurate diagnosis as well as better prognosis of outcome and recovery, leading to improved healthcare wellbeing.