Health Data Research UK’s Understanding the Causes of Disease programme aims to help advance understanding of disease prediction, causation, and
progression through the integration of molecular data and other intermediate phenotypes with routine clinical data.
The overarching hypothesis is that insights into biology and disease aetiology can be revealed by integration of information, at scale, on genomics, other biomolecular traits, and high-resolution electronic health records (EHRs).
The ultimate vision is to create new informatics infrastructures and data science methods that help achieve a deep integration of biology, biomedicine, and population health science.