Characterising a healthy adult with a rare HAO1 knockout to support a therapeutic strategy for primary hyperoxaluria
24 March 2020
McGregor TL, Hunt KA, Yee E, Mason D, Nioi P, Ticau S, Pelosi M, Loken PR, Finer S, Lawlor DA, Fauman EB, Huang QQ, Griffiths CJ, MacArthur DG, Trembath RC, Oglesbee D, Lieske JC, Erbe DV, Wright J, van Heel DA.
eLife (2020) 9
Association of troponin level and age with mortality in 250 000 patients: cohort study across five UK acute care centres
21 November 2019
Kaura A, Panoulas V, Glampson B, Davies J, Mulla A, Woods K, Omigie J, Shah AD, Channon KM, Weber JN, Thursz MR, Elliott P, Hemingway H, Williams B, Asselbergs F, O’Sullivan M, Kharbanda R, Lord...
Associations of genetically determined iron status across the phenome: A mendelian randomization study
20 June 2019
Dipender Gill, Beben Benyamin, Luke S. P. Moore, Grace Monori, Ang Zhou, Fotios Koskeridis, Evangelos Evangelou, Mike Laffan, Ann P. Walker, Konstantinos K. Tsilidis, Abbas Dehghan, Paul Elliott,...
Carotid Intima-Media Thickness: Novel Loci, Sex-Specific Effects, and Genetic Correlations With Obesity and Glucometabolic Traits in UK Biobank
1 February 2020
This study looked at the amount of fatty deposits on blood vessel walls in over 22,000 individuals, to work out how small differences in their DNA might cause heart disease. They found some...