We all vary in how our bodies handle medicines and many of these differences are inherited from our parents. Pharmacogenetics is the science of understanding these inherited differences, and whether medicines will work like they are meant to or cause side effects.

For some medicines there is now good evidence that choice of medicine or dose should be guided by knowledge of each person’s inherited drug metabolism. The aim of this project is to develop systems to make prescribing more tailored to individuals, starting by implementing pharmocogenetic prescribing in a number of practices to evaluate whether it improves patient outcomes.