CVD-COVID-UK focuses on heart and circulatory disease research, whilst COVID-IMPACT focuses on other health conditions. Both projects aim to answer three broad questions (see the protocol for more detail):
- What are the effects of heart and circulatory diseases or other prior health conditions, their risk factors and medications on susceptibility and poor outcomes (including admission to hospital, requirement for intensive care and death) from COVID-19 disease?
- What is the direct impact of COVID-19 on heart and circulatory disease complications or on other health complications, as well as on medium and longer-term heart and circulatory disease or other health condition risks?
- What is the indirect impact of the COVID-19 pandemic and the government and NHS response to it on the presentation, diagnosis, management and outcomes of heart and circulatory diseases or other health conditions?