From an early background in natural sciences, urban planning and geography, Andrew Pickles joined the MRC Child Psychiatry Unit as statistician in 1986, moved to the Dept of Biostatistics in Manchester in 1998, returning to the IoPPN in 2010.
His principal interests have been in multivariate longitudinal data, with most applications being in what is now called life-course analysis. These studies have involved genomic, physiological, psychological and social measures and processes and have spanned neonates to geriatrics. A good part of this work has focused on autism, with recent work highlighting intervention studies and longer term outcomes.

Equally rewarding have been the impact on statistical modelling and software (e.g. structural equation modelling in Stata) and the clinical impact on patient care (e.g. NICE guidelines).