Lead organisation: University Hospitals Birmingham NHS Foundation Trust
Hub Director: Professor Alastair Denniston, a.denniston@bham.ac.uk

There is an increasing demand for ‘big data’ to enable innovation in health technologies and improve patient care. INSIGHT creates an NHS-academic-industry partnership to make anonymised datasets accessible and provide critical services that respond to user needs (patients/industry/other),  including ‘real-world evidence’ and ‘smart’ clinical trials for new drugs or devices, and accelerating AI-algorithm development for the NHS and beyond.

INSIGHT is focused on eye disease and its application to wider health, including diabetes and dementia. INSIGHT turns routine eye imaging – currently >25million/yr (UK) – into an exceptional asset for innovation as a convenient, uniquely valuable health snapshot.

INSIGHT uses anonymised large-scale data and advanced analytics to bring new clinical insights: from detection, diagnosis and referral, to new treatments and personalised healthcare. INSIGHT unlocks this opportunity by pairing unique anonymised data assets to hubs of expertise where patients and clinicians can, with industry, more efficiently explore the safety and use of new AI systems. This will accelerate the pace with which AI is able to translate to real patient benefit for the NHS and accelerate innovation across all sectors.

Prof Alastair Denniston, Consultant Ophthalmologist – University Hospitals Birmingham and University of Birmingham, and Director of INSIGHT:

“Sight is the most precious of all the senses and yet in the UK around 2 million people live with sight loss. As an eye doctor, I am dedicated to working with the whole community to improve treatments for people with sight-threatening conditions like age-related macular degeneration and diabetic eye disease. I have also seen how our incredible imaging technologies can be used to identify and predict diseases beyond the eye such as dementia or heart disease.

INSIGHT is about using the power of health data and the development of artificial intelligence solutions to tackle blinding diseases and other serious conditions. INSIGHT will be a resource that will accelerate our understanding of disease and enable us to detect disease earlier, personalise care and accelerate the development of new therapies.”

Dr Wen Hwa Lee, CEO Action Against AMD, who also represents Blind Veterans UK, Fight for Sight, Macular Society and Scottish War Blinded:

“We welcome Health Data Research UK’s and INSIGHT’s ground-breaking initiative to include patients and public in transparently deciding how health data can be used. This is a great way to establish trust among all stakeholders, who can create together the future of eye health and possibly even other conditions.”

Partners involved in INSIGHT: University Hospitals Birmingham NHSFT (lead institution) | Moorfields Eye Hospital NHSFT | University of Birmingham | Roche | Google | Action Against AMD (Fight for Sight, Macular Society, Blind Veterans UK, Scottish War Blinded, Royal Blind)